The book entitled PHARMACEUTICAL TECHNOLOGY (Solid Dosage Form ) discusses about pharmaceutical technology that involves the rational design and manufacture of oral solid dosage forms. This book provides an understanding of the links between formulation theory and the practicalities of processing in a commercial environment, giving researchers the knowledge to produce effective pharmaceutical products that can be approved and manufactured. This book also covers the essential principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their application to the research and development process of oral dosage forms. The book introduce readers to different oral solid dosage forms such as powders, tablets and capsules. The book illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in formulation, process design, characterization, scale-up, and production operations. This book is an attempt to comprehensively present, in a single book, various pharmaceutical processes and equipment that are frequently used for production of oral solid dosage forms, along with quality control tests of these dosage forms. Pictorial/graphical illustrations provide easier understanding of complex pharmaceutical concepts, manufacturing processes of pharmaceutical dosage forms.

CONTENTS

1. POWDER………………………………Page . 11
1)Introduction to powder
2)Standards of powders
3)Classification of powders
4)Process flow of powder manufacturing
5)Layout of powder manufacturing
6)Quantitative layout for powder manufacturing
7)Equipment involved in powder manufacturing as per GMP
Milling, Sieving, Mixer
Drying equipment & Filling equipment
8)Packaging of powders
9)Quality control of the powder
10)Validation
11)Documentation
12)Master formula record
13)Batch manufacturing record
14)Batch packaging record
15)Problems associated with powder manufacturing
16)Hazards of powder manufacturing
17)Powder processing
18)Powder recovery system
19)Innovations in powder dosage form
20)List of pharmaceutical powders available in market

2. TABLET - SOLID DOSAGE FORM……………Page. 51
1)Introduction
2)Properties of tablet dosage forms
3)Classification of tablets
4)Preformulation aspects of tablet
5)Granulation
6)Mechanisms of granule formation
7)Types of granulators
8)Tablet compression machine
9)Physics of tablet compression
10)The process of compression
11)Heckel equation
12)Problems of tablet
13)Evaluation of tablet
Uniformity of content of active ingredient
Disintegration, Dissolution and Friability test
14)Plant layout & Objectives of plant layout
15)Pharmaceutical factory layout and planning
16)Validation
17)Documentation
18)Batch manufacturing record
19)Master formula
20)Batch packaging record
21)Manufacturing requirements & precaution

3.TABLET COATING ………………………..Page. 194
1)Introduction
2)Need for tablet coating
3)Basic principle of tablet coating
4)Type of tablet coating process
5)Sugar-coating of tablets
6)Film coating
7)Enteric coating
8)Processing problems and remedies for tablet coating

4.CAPSULE……………………………………….Page. 227
1.Introduction
2.Types of capsule
3.Hard gelatin capsules (Dry filled capsules)
4.Manufacturing of hard gelatin capsules shells (empty)
5.Dimensions of hard gelatin capsules shells
6.Preparation of filled hard gelatin capsules
Formulation
Capsules shell feeling
Capsule sealing
Cleaning and polishing
7.Process flow diagram for automated capsule filling
8.Problems in capsules filling and remedies thereof
9.Soft gelatin capsules
10.Manufacturing process of soft gelatin capsules
11.Automatic capsule filling transfer line
Fce – 100 filled capsule elevator
Af – 90 (t) – automatic capsule filling machine
Adu-100 air displacement unit
Dp- 100 de – dusting and polishing machine
Mcs 100 mini capsule sorter
12.Filling of capsule
13.Technical specifications
14.Packaging
15.Storage
16.Quality control tests
17.Evaluation of capsules
18.Packaging and labeling of capsules
19.Novel technology in capsule formulation

BIBLIOGRAPHY………………………………….Page. 294