Description
The mucosal surfaces of the human body, including those found in the oral, nasal, ocular, pulmonary, gastrointestinal, and vaginal regions, offer unique and promising pathways for drug delivery. These surfaces are characterized by their rich blood supply, extensive surface area, and permeability, making them ideal for rapid and efficient drug absorption. The development of mucosal drug delivery system has revolutionized the field of pharmaceutical sciences, providing alternatives to traditional drug administration routes and offering solutions for drugs that are poorly absorbed, rapidly metabolized, or degraded in the gastrointestinal tract.
Mucosal Drug Delivery System is an exploration of the latest advancements, methodologies, and applications of this cutting-edge technology. This book is intended for researchers, pharmaceutical scientists, and healthcare professionals who are interested in the development and implementation of innovative drug delivery strategies. By compiling the most recent research and developments in this field, we aim to provide a comprehensive resource that covers the fundamental principles, challenges, and future directions of mucosal drug delivery.
The content of this book is organized into several key sections. We begin with an overview of the anatomical and physiological characteristics of various mucosal surfaces, providing the foundational knowledge necessary for understanding the complexities and opportunities of these drug delivery routes. Subsequent chapters delve into the design and formulation of mucoadhesive systems, including the selection of bioadhesive polymers, drug release mechanisms, and the evaluation of bioadhesive strength.
Case studies and real-world applications are also presented, highlighting the successful development and clinical use of mucosal drug delivery systems. These examples illustrate the potential of these systems to improve patient compliance, enhance therapeutic outcomes, and provide targeted delivery of a wide range of therapeutic agents. Additionally, the book discusses regulatory considerations and the future landscape of mucosal drug delivery, offering insights into the pathways for bringing these innovative products to market.
As the field of mucosal drug delivery continues to evolve, new challenges and opportunities will arise. It is our hope that this book will serve as a valuable reference for those engaged in the research and development of these systems, inspiring further innovation and collaboration. We are grateful to the many contributors who have shared their expertise and insights, and we look forward to the continued advancement of mucosal drug delivery technologies.
We trust that Mucosal Drug Delivery System will provide you with a thorough understanding of this exciting field and stimulate further research and development in the pursuit of more effective and patient-friendly drug delivery solutions.
1)Dr. Harshal Ashok Pawar M. Pharm., PhD, MD (AM)
He is currently working as an Assistant Professor with Dr. L. H. Hiranandani College of Pharmacy, Ulhasnagar, Maharashtra (Affiliated to University of Mumbai, India). He has also worked as a Head of Department of Quality Assurance for six years. He has 19 years of teaching cum industry research experience. He worked with various pharmaceutical industries like Medley, Charak and Alkem Research Centre. He has published more than 80 research and review articles in various national / international journals of repute. He has also presented various research papers in national / international conference, seminars, symposia and workshops. He has five Indian and three international patents to his credit. He has received research grants for various projects from University of Mumbai. He is on editorial board and reviewer for many international journals. He has guided 30 M. Pharmacy Research scholars in the subject of Quality Assurance. He is also recognized PhD guide of University of Mumbai, Pacific University and Mansarovar University. He has authored more than 10 books in the field of Pharmaceutical Sciences.
2) Mr. Girish Nihalani M. Pharm.
He is a Research Fellow of Product Development at Teva Pharmaceuticals based at Florida, USA. Mr. Nihalani earned his Master’s Degree in Pharmaceutical Sciences from Bombay College of Pharmacy in 2005; thereafter has dedicated his career in formulation development of Modified Release Solid Oral Dosage forms for international markets. Over years, Mr. Nihalani has developed multiple complex drug products as ANDA including first to file, first to market, NCE-1 and 505(b)2. He has specific interests in amorphous dispersions, multiarticulate and matrix-based dosage forms. He has received recognition and awards by his employers for his exceptional performance.
Mr. Nihalani has held professional positions of increasing prominence for globally renowned companies, such as Actavis Inc., Cipla Inc., Watson Inc., Dr. Reddy’s Laboratories, FDC Limited and Inventia Healthcare Ltd. In his current role at Teva Pharmaceuticals, he continues to lead development of BCS class II and IV modified release drug products requiring expertise in formulation development and biopharmaceutics.
Mr. Nihalani to his name has multiple publications including three patent applications. He is a member of AAPS, serves as reviewer of peer reviewed journals such as AAPS, Journal of Pharmaceutical Science (JPS), Journal of Controlled Release (JCR). He has poster presented at annual conferences of Controlled Release Society (CRS) and AAPS.
3) Dr. Hitendra S. Mahajan M. Pharm., PhD
He is working as a Professor and Head Department of Pharmaceutics at R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur (M.S). He has 23 years of teaching and research experience. He earned his B. Pharm (1994) from North Maharashtra University Jalgaon, M. Pharm (2002) from Shivaji University Kolhapur, and PhD (2010) from North Maharashtra University, Jalgaon. He is the recipient of the Research Award from the University Grant Commission, New Delhi, and Prof. Ambikanandan Misra Research Excellence Award in Pharmaceutics and Drug Delivery Award-2019, Association of Pharmacy Teachers, India (APTI). Prof. M. M. Sharma Prize for Science and Technology from Marathi Vidnyan Parishad, Excellent Teacher Award (2018), Research (Funding) award (2022), Research (Publication) award (2023) from KBC North Maharashtra University, and Nation Builder Award from Rotary International.
He has more than 150 publications in journals of repute and holds 02 Indian patents on his research work. He completed four research projects of Rs. 144.00 lakhs from various funding agencies such as AICTE, UGC, SERB, BIRAC, ICMR, and Rajiv Gandhi Science Technology Commission, Govt of Maharashtra. He is elected Chairperson Board of Studies (Pharmaceutics) Kavayitri Bahinabai Chaudhari North Maharashtra University, Jalgaon.
ISBN: 9789395178761
Publisher: Aarya Publishing House, Maharashtra, India
Number of Pages: 204
Dimensions: 6.00"x9.00"
Interior Pages: B&W
Binding:
Paperback (Perfect Binding)
Availability:
In Stock (Print on Demand)