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Disease Management is an approach to manage care that co-ordinates resources across the entire care delivery system and throughout life cycle of disease. Herbal medicines derived from plant extracts are being increasingly utilized to treat a wide variety of diseases, although relatively modest acquaintance about their mode of action is existing. There is an emergent interest in the pharmacological evaluation of various plants used in Indian traditional systems of medicine. Thus, in the present investigation, an attempt was made to evaluate the anti-ulcer (Aphthous stomatitis) activity using Liquorice and Catechu Lozenges (LC-LOZ).
This book provides a currently locally acting formulation to treat recurrent aphthous stomatitis (RAS). Lozenges are one of the locally acting palatable oral formulations that may be used for the treatment of RAS. The aim of the present research work was to formulate locally acting efficacious herbal lozenges for the treatment of RAS which can provide a good patient compliance. As the part of preformulation study, estimation of secondary plant metabolites (Total phenolics and flavanoids) and compatibility study was carried out to formulate lozenges by moulding method. In in- vitro study on LC-LOZ demonstrated the depression of inflammation. Prior to the initiation of human clinical trials of novel drugs, the safety of their application is to be proved.
Mrs. Kesha M. Desai [M.pharm., Ph.D*]
Oxford College of Pharmacy Bangalore,