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Artificial intelligence (AI) is a type of digital computer system that parallels the way the human brain processes information. AI is organized in a similar way that neurons in the brain are arranged, with their multiple neural nodes, and so are referred to as neural networks. Nonetheless, the use of AI for health presents transnational ethical, legal, economic, and societal challenges. Many of these problems are not specific to artificial intelligence. For more than a half-century, the use of software and computing in health care has presented issues to developers, governments, and providers, and AI presents new, fresh ethical challenges that reach beyond the jurisdiction of traditional regulators and participants in healthcare systems. If AI is to be broadly deployed to promote human health, protect human autonomy, and provide equal access to such technology, these ethical problems must be effectively addressed.