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Language is a medium of communication. The set of instructions given to computers to do its work is called programming language. Computer programming languages are developed with the primary objectives of facilitating a large number of people to use computer without the need to know the details of internal structure of the computer. Using set of instructions or statements the users can develop a program or software which is called programming.This book provides the knowledge of JAVA language as applicable to Bioinformatics and Computational Biology field.