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FORMULATION & EVALUATION OF PULSATILE RELEASE TABLET OF PITAVASTATIN CALCIUM

Miss. Bhoomi Rawal, Mr. Ajay Talele, Mr. Harshiv Naik
Type: Print Book
Genre: Medicine & Science
Language: English
Price: ₹299 + shipping
Price: ₹299 + shipping
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Description

Pitavastain increases the level of the HDL-C as compared to the other statins. Pitavastatin is a stronger inhibitor of HMG-COA reductase enzyme than other statin. Pitavastatin shows fewer side effects (Muscle pain, stomach upset, and headache). Compared to other statins. Pitavastatin is grater bioavailability as compared to other statin. Pitavastatin is a low dose as compare to other statin. Cholesterol synthesis get increased late night and early morning so there is need of drug action which reduces cholesterol level at that time.So to deliver drug in above situation pulsatile drug delivery system can be appropriate. Drug releases after a desired lag time. By direct delivery of the drug to intestine side effects related to stomach were reduced. Using pulsatile drug delivery system first pass metabolism may be avoided. To increase the solubility of the Pitavastatin calcium better drug release after erosion of pulsatile coating layer. This work in book will helpful to all students and researcher plans to work in this different type of dosage form in section for development.

About the Authors

Miss Bhoomi Rawal [M. Pharm.] Smt. BNB. Swaminarayan Pharmacy college Salvav, Vapi.

Mr. Ajay Talele [M. Pharm.]
Assistant Professor
Smt. BNB. Swaminarayan Pharmacy college Salvav, Vapi.

Mr. Harshiv Naik B.Pharm
Smt. BNB. Swaminarayan Pharmacy college Salvav, Vapi.

Book Details

ISBN: 9789384097301
Publisher: Pharmamedix India Publication Pvt. Ltd.
Number of Pages: 118
Dimensions: 5"x8"
Interior Pages: B&W
Binding: Paperback (Perfect Binding)
Availability: In Stock (Print on Demand)

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