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The objective of the book was to provide the students and teachers, a
text which will fulfil their specific requirements of the drug
candidatures for selection of suitable dosage form.
During the past years, buccal drug delivery has attracted the
attention of researchers looking for alternative delivery routes of
administration. As an alternative to oral drug delivery, the buccal
mucosal route avoids the passage through the acidic gastric
environment, intestinal and bacterial enzymatic activity, and first pass
metabolism of the liver. Therefore, the buccal route could be a good
delivery route for macromolecules and other drugs not compatible
with the gastrointestinal tract environment.
This buccal drug delivery special edition of drug development
and industrial pharmacy aims to bring together a range of different
aspects relevant to the growing field of buccal drug delivery. The
special edition includes through reviews of the literature, as well as
original articles touching on most prominent features related to buccal
drug delivery systems, such as the move toward the use of
nanotechnology in different ways to facilitate buccal drug delivery
with the potential to prompt future product developments.
I am extremely thankful to all the persons who have helped
me in writing this book especially, Miss. S. Shalini and D. Karthik
I am indebted to Professor Madhusudan Rao Yamsani (my
guide, Kakatiya University, Warangal) in extending their valuable
advice for completion of this book.